After applying the inclusion and exclusion criteria,there were six eligible articles. PubMed, Proquest, and Scopus were used to find articles which investigate the association between diversity of MTB genotype and drug resistant. Methods: A literature search was conducted in several electronic databases. The Multidrug resistance TB is of ten linked to the diversity of Mycobacterium tuberculosis genotype.This study aimed to investigate whether diversity of genetic profile M.tuberculosis influenced the drug resistance. Drug resistant become the hardest challenge to cure this disease. Introduction: Tuberculosis (TB) remains as ignificant global health problem,but it is possibly curable when TB is detected and effectively treated. 1Faculty of Medicine, Universitas IndonesiaĢRespirology and Critical Illness Division, Internal Medicine DepartmentĬipto Mangunkusumo Hospital/ Faculty of Medicine Universitas Indonesia
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